Harlequin cells

Harlequin cells
Author: Luiz Arthur Leite, PhD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016)
Published Date: 08/17/2023

Eosinophils with large purple-violet granules resembling basophilic granules. Dysplastic eosinophils with metachromatic granules are often referred to as harlequin cells, which are commonly observed in acute myeloid leukemia (AML) with inv(16)(p13.1q22) or t(16;16)(p13.1;q22) and chronic myeloid leukemia. May-Giemsa staining of bone marrow examination).