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foam cell in Niemann-Pick patient

foam cell in Niemann-Pick patient
#00064804
Author: Najmaldin Saki, PhD; Fatemeh Bakhshpour M.Sc; Zeinab Eftekhar M.Sc; Bita Bandar M.Sc
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Histiocyte/macrophage – storage disease > Niemann Pick  
Published Date: 11/15/2023

A 3-year-old female child patient presented with pancytopenia. His bone marrow aspirate smear showed cluster of foam cells having round nuclei and cytoplasm containing clear vacuoles of varying size and soap-bubble appearance. Enzyme studies confirmed the diagnosis of Niemann-Pick disease.