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BPDCN and CMML - bone marrow aspirate 1

BPDCN and CMML - bone marrow aspirate 1
#00065318
Author: Min-Hi Han; Penny A Wright; Sean A MacPherson; Peter S Ganly
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Blastic plasmacytoid dendritic cell neoplasm
Published Date: 09/20/2024

Bone marrow examination revealed a  hypercellular marrow with blasts with blue-grey cytoplasm with microvacuolation (“string of pearls”) around the periphery, with distinct tail-like protrusions (pseudopodia). Mild trilineage dysplasia was noted without expanded myeloblasts, consistent with concurrent CMML-1.