CSF myeloid blast crisis with frank basophilia in patient of CML, on therapy. 3

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CSF myeloid blast crisis with frank basophilia in patient of CML, on therapy. 3

#00065668

Author: Sanjoli Chugh; Gaurav Chatterjee
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myeloproliferative Neoplasms (MPN) > Chronic Myelogenous Leukemia (CML), BCR-ABL1+ > Blast phase > Extramedullary blast proliferation
Published Date: 02/27/2026

Figure 3. Panel of Flow cytometry plots shows abnormal myeloid blasts in red color gated at 8.33% of all the viable cells show bight CD34, overexpression of HLADR, CD45 Dim, CD38 Moderate , CD56 Negative, CD13 Mod-Dim, CD15 Negative, CD33 Variable CD117 Variable, CD36 Dim, CD64 Moderate, CD14 Negative, CD19 Negative, CD123 Moderate, CD203 Variable and moderate expression of CD7. A subset of the blasts show bright expression of CD117 indicating Mast cell differentiation(Black) and is negative for CD9, CD2, CD41 and CD33. In addition, an expanded population of basophils(green) gated at 90.36% of all the viable cells show moderate CD45, CD123, CD38, CD203c, variable CD33 and negative HLADR

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