Blasts in AML

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Blasts in AML

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Author: Gurpreet Kaur, MD,DM; Ankur Ahuja , MD, DM; Somasundaram Venkatesan, MD, DM
Category: Myeloid Neoplasms and acute leukemia (WHO 2016)
Published Date: 07/08/2025

Blasts in AML are moderate to large sized with a high nuclear-to-cytoplasmic ratio, irregular nuclear contour, and smooth chromatin with prominent or multiple nucleoli. These blasts typically have cytoplasm that appears pale or deep blue with a variably eosinophilic hue and Auer rods as is shown in the picture here.

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