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IgM myeloma-triggered HLH

IgM myeloma-triggered HLH
#00066050
Author: Ke Xu, MD
Category: Macrophage/Histiocytic and dendritic cell Neoplasms and disorders (2015) > H group > Secondary HLH (non-Mendelian)
Published Date: 12/04/2025

The bone marrow smear of a patient with relapsed IgM myeloma with t(14;16) shows haemophagocytosis, red cell rouleaux (upper panels, May-Grünwald-Giemsa stain x100 objective), and atypical plasma cells, background staining (lower panels, May-Grünwald-Giemsa stain x40 objective).  Hb 86g/L, WBC 1.1x10^9/L, platelet 48x10^9/L and IgM paraprotein 19g/L.

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