Advertisement intended for health care professionals

l

Hand-Mirror Lymphoblasts in T-Cell Acute Lymphoblastic Leukemia 1

Hand-Mirror Lymphoblasts in T-Cell Acute Lymphoblastic Leukemia 1
#00066150
Author: Yehezkiel Yonathan; Ratu Purwanti
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Precursor Lymphoid Neoplasms > T-lymphoblastic leukemia/lymphoma > Early T-cell precursor lymphoblastic leukemia (provisional)
Published Date: 04/16/2026

Bone marrow smears stained with Wright–Giemsa showed a predominance of medium-to-large lymphoblasts with a high nuclear-to-cytoplasmic ratio, round to mildly irregular nuclear contours, and coarse chromatin. The cytoplasm was scant to moderately basophilic. A subset of blasts exhibited characteristic hand-mirror cell morphology, defined by a thin, elongated, lightly basophilic cytoplasmic tail clearly separated from the nuclear mass, resulting in a markedly asymmetric cellular contour. No Auer rods or cytoplasmic granules were identified.

Advertisement intended for health care professionals