Giant Pronormoblast: A Hallmark of Parvovirus B19 Infection

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Giant Pronormoblast: A Hallmark of Parvovirus B19 Infection

#00066199

Author: Tejasvi Sharma; Abhishek Purohit; Kanchan Thakur
Category: Underproduction Anemias > Pure Red Cell Aplasia
Published Date: 02/04/2026

Bone marrow aspirate smear reveals a giant pronormoblast with a round nucleus, finely dispersed chromatin, and deeply basophilic cytoplasm with multiple cytoplasmic blebs ("dog-ear" appearance), a classic morphological hallmark of parvovirus B19 infection. Serologic testing confirmed parvovirus infection in the patient. (Wright-Giemsa stain, oil immersion view.)

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