Ghost Histoplasma: Residual Intracellular Yeasts Following Therapy

Main Navigation
Account Navigation
Main Content

JavaScript is disabled on your browser

Please enable JavaScript or upgrade to a JavaScript-capable browser to use the ASH Image Bank.

COLLECTION

Images of peripheral blood and/or bone marrow of blood disorders and normal hematopoiesis.
ATLAS

Normal and abnormal blood cells
REFERENCE CASES

Complete cases of common blood disorders (peripheral blood, bone marrow, and diagnostic studies).
UPLOAD IMAGES

Ghost Histoplasma: Residual Intracellular Yeasts Following Therapy

#00066544

Author: Pratyush Mishra; Anil Handoo; Tina Dadu; Aditi Mittal
Category: Infectious Disease > Fungi > Histoplasmosis
Published Date: 10/02/2026

Microscopic examination of bone marrow aspirate smears reveal clusters of histiocytes containing multiple intracellular fungal organisms (A & B). On H&E staining, the yeasts appear as small, uniform, oval inclusions within histiocyte cytoplasm (C). GMS stain distinctly highlights the organisms, confirming their fungal nature (D). The overall morphologic findings are consistent with Histoplasma capsulatum infection.

Download Image