Extreme thrombocytosis in CML

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Extreme thrombocytosis in CML

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Author: Shaun Chew, MBBS; Yogesh Jeelall, MD PhD; Matthew Wright, FRCPA FRACP
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myeloproliferative Neoplasms (MPN) > Chronic Myelogenous Leukemia (CML), BCR-ABL1+
Published Date: 06/29/2026

Extreme thrombocytosis (platelet count 5,018 x 10⁹/L) accompanied by severe basophilia (basophil count 2.2 x 10⁹/L) on peripheral blood film from a 73-year-old lady with chronic myeloid leukaemia. Of note, haemoglobin was 92g/L, absolute neutrophil count 7.0 x 10⁹/L, absolute lymphocyte count 2.4 x 10⁹/L, and monocyte count 1.2 x 10⁹/L.