AML with biallelic CEBPA mutation with biZIP: flow cytometry

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AML with biallelic CEBPA mutation with biZIP: flow cytometry

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Author: Ke Xu, MD; Natalina Cucinotta
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with mutated CEBPA
Published Date: 10/02/2026

Flow cytometry showed 90% blasts. They were positive for CD34, CD117, HLADR, CD33, CD7, CD56 and cMPO. AML with a biallelic CEBPA mutation with biZIP has a favourable prognosis. The leukemic cells are often positive for CD7, but they rarely express CD56 or CD14.

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