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Mixed phenotype acute leukemia with t(v;11q23); MLL rearranged.

Author: Elizabeth L. Courville, MD, 10/02/2015
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute leukemias of ambiguous lineage > Mixed phenotype acute leukemia with t(v;11q23); KMT2A rearranged
Published Date: 02/25/2016
     
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54 year old female.

Flow cytometry of the bone marrow specimen identified a blast population with the following immunophenotype:  positive for CD3 (cytoplasmic), CD7, CD34, CD13, CD33, CD117, and myeloperoxidase (MPO). An 11q23 abnormality (MLL) was identified by cytogenetic analysis.