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Mature schizont of Plasmodium vivax in peripheral blood

Author: Shilpi Saxena, MD; Smriti Garhwal; Ritu Mehta, 10/09/2026
Category: Infectious Disease > Parasites > Malaria > P. vivax
Published Date: 10/15/2026

Plasmodium vivax undergoes asexual reproduction within erythrocytes through successive ring, trophozoite, and schizont stages. During schizogony, nuclear division and cytoplasmic segmentation produce multiple merozoites within the infected erythrocyte (as shown in figures). Mature schizonts typically contain 12–24 merozoites, with aggregated yellowish-brown malarial pigment. Infected erythrocytes are often enlarged. Following schizont maturation, erythrocyte rupture releases merozoites that preferentially invade reticulocytes, perpetuating the blood-stage infection. Thus, multiple merozoites enclosed within an erythrocyte represent a mature schizont (as shown in figures). Recognition of accompanying erythrocyte changes and other characteristic parasite stages supports morphological identification of P. vivax on peripheral thin blood smears.

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