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Plasma cell myeloma - Russell bodies

Plasma cell myeloma - Russell bodies
#00010938
Author: Joo Y. Song
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Plasma Cell Neoplasm
Published Date: 05/03/2012

The patient is a 63 year-old male found to have lytic bone lesions. An IFE/SPEP was performed and showed an M-spike that was IgA lambda. A bone marrow biopsy was performed and showed numerous round globules in both the aspirate and core biopsy. The plasma cells were positive for CD138 . The aspirate smear shows occasional cytoplasmic round bodies within plasma cells, characteristic of Russell bodies.