Author: Teresa Scordino MD
Category: Morphologic variants of normal cells > Morphologic variants of white blood cells
Published Date: 02/17/2016

Neutrophilic metamyelocytes have condensed chromatin and a slightly indented nucleus (the indentation is less than half the diameter of the nucleus). The cytoplasm contains abundant specific granules and rare primary (azurophilic) granules.  Metamyelocytes are not normally present in the peripheral blood, but can be seen in infectious or inflammatory states, and in other reactive and neoplastic conditions.