Author: Teresa Scordino MD
Category: Morphologic variants of normal cells > Morphologic variants of white blood cells
Published Date: 02/17/2016

Promyelocytes are larger than myeloblasts, and have basophilic cytoplasm containing primary (azurophilic) granules.  A Golgi zone may be visible as a paranuclear hof or clearing.  The nuclear chromatin is finely dispersed, and nucleoli may be visible.  Promyelocytes comprise approximately 2% of nucleated cells in the bone marrow and do not circulate in peripheral blood under normal conditions.