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Promyelocytes are larger than myeloblasts, and have basophilic cytoplasm containing primary (azurophilic) granules. A Golgi zone may be visible as a paranuclear hof or clearing. The nuclear chromatin is finely dispersed, and nucleoli may be visible. Promyelocytes comprise approximately 2% of nucleated cells in the bone marrow and do not circulate in peripheral blood under normal conditions.