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Lymphoma with Auer Rods

Lymphoma with Auer Rods
#00061481
Author: Angie Duong, MD
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms
Published Date: 06/14/2018

Wright-Giemsa, 60x.  Peripheral blood smear with lymphocytosis.  Lymphocytes are intermediate in size with round nuclei, clumped chromatin, and moderate amounts of basophilic cytoplasm.  Interestingly, several of the lymphocytes contain fine, eosinophilic crystalling Auer-rod like structures rods.  Concurrent flow cytometry showed a monoclonal B-cell population.

 

These structures are consistent with immunoglobulin and such eosinophilic accumulations of immunoglobulin may be seen frequently in low-grade B-cell lymphomas, frequently lymphoplasmacytic lymphoma