PD-L1/PAX5 dual immunostaining in Reed-Sternberg cells

PD-L1/PAX5 dual immunostaining in Reed-Sternberg cells
#00064058
Author: Abhishek Dashora MD, FRCPath
Category: Lymphoma: Hodgkin Lymphoma
Published Date: 06/07/2022

Double immunostaining in classical Hodgkin Lymphoma showing Reed-Sternberg cells expressing membranous PD-L1 and weak nuclear PAX5. Background normal small B-cells express strong nuclear PAX5.

Background reactive histiocytes typically express moderate-strong PD-L1 serving as internal controls.