Apoptotic lymphocyte 3

Apoptotic lymphocyte 3
Author: Isil Erdogan Özünal, MD
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells
Published Date: 05/19/2023

Apoptotic lymphocytes on peripheral blood. These are from a patient diagnosed with hairy cell leukemia and treated with 2-chlorodeoxyadenosine (cladribine, 2CDA).  After 2 weeks of the treatment initiation, apoptotic lymphocytes were detected on the blood film. Note the nuclear shrinkage, nuclear condensation, and fragmentation. May-Grünwald Giemsa stain.