#00064764

A 73-year-old patient diagnosed with multiple myeloma presented with an IgG monoclonal component level of 6.3 g/L, a bone marrow infiltration of plasma cells at 15%, and myeloma-defining features including anemia, lytic bone lesions, and a bulky plasmacytoma in the humeral region (Figure A and B) that led to a pathological fracture and compression of surrounding tissues (Figure C and D).

She underwent a treatment regimen consisting of Bortezomib, Lenalidomide, and dexamethasone, complemented by localized radiotherapy. This was followed by consolidation therapy involving high-dose melphalan and autologous stem cell transplantation, which resulted in a complete response with complete eradication of the tumor mass (as shown in Figure E). As of today, she has been on lenalidomide maintenance therapy for 17 months.