APML with Auer Rods; Flow cytometry 1

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APML with Auer Rods; Flow cytometry 1

#00065416

Author: Charlotte Pattison, MSc
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with t(15;17)(q22;q12); PML-RARA (and variants)
Published Date: 10/31/2024

57yo female presented in A/E with pancytopenia of unknown cause, thought to be due to bone marrow failure - so bone marrow aspirate was taken and investigated on.

APML seen in images - promyelocytes with many Auer rods in the cytoplasm.

These promyelocytes characterised by flow as CD117+ CD24- HLADR- CD33+ CD9+ CD13+ CD15+ cMPO+

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