EDTA-Dependent severe pseudothrombocytopenia

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EDTA-Dependent severe pseudothrombocytopenia

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Author: Oussama Grari, MD,PhD; Hamid Ouhnini; Amina Himri; Abdelilah Berhili; Nabiha Trougouty; Mounia Slaoui; Assya Khermach; Mohammed Bensalah; Rachid Seddik
Category: Laboratory Hematology > Basics of automated cell counts > Causes of inaccurate platelet counts > Falsely low platelet counts > Platelet clumps
Published Date: 12/30/2024

Peripheral blood smear from a 1-year-8-month-old male with severe thrombocytopenia on an EDTA tube, showing a platelet count of 23,000/µL. Multiple platelet clumps are visible, causing pseudothrombocytopenia. Repeating the CBC on a citrate tube corrected the platelet count to 207,900/µL.

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