Cold agglutinin disease 1

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Cold agglutinin disease 1

#00066055

Author: Sumitha Baskaran; Madhura Jogwar; Amit Taori; Sanjay Gohil; Metropolis healthcare limited; Abhay Bhave; Shrinath Kshirsagar; Gleneagles hospital Mumbai
Category: Red Cell: Hemolytic Anemia (HA) > Autoimmune Hemolytic Anemias > Cold-active antibodies > Cold agglutinin disease (CAD) > Secondary CAD
Published Date: 12/19/2025

Peripheral blood smear showing extensive cold-induced red cell agglutination, with large clusters and irregular aggregates of erythrocytes throughout the field. (Wright–Giemsa stain, 400×)