Microscopic image analysis of core liver biopsy

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Microscopic image analysis of core liver biopsy

#00066329

Author: Rosa Park; Yang Shi; Yanhua Wang
Category: Lymphoma: Mature T and NK cell lymphoproliferations > Mature T-cell Lymphomas > Gastro-intestinal T-cell lymphomas > Hepatosplenic T-cell Lymphoma
Published Date: 05/01/2026

(A) H&E staining of the core liver biopsy demonstrates mildly dilated sinusoids containing a few medium‑ to large‑sized lymphocytes (yellow arrowheads), 40×. (B–D) Immunohistochemistry shows sinusoidal lymphocytes positive for CD3 (B), negative for CD5 (C), and partially positive for CD8 (D), all at 40×.