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GZL CD-15

GZL CD-15
#00063801
Author: Arun Ravi; Girish Venkataraman, MD, MBBS
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Large B-cell lymphomas (not Richter transformation) > B-cell lymphoma unclassifiable with features intermediate between DLBCL and cHL
Published Date: 10/19/2021

CD 15 is confirmatory for the diagnosis of Hodgkin lymphoma. These atypical cells have abundant cytoplasm, and the nuclei often contained prominent nucleoli. Typical Reed-Sternberg cells (large B cells) are seen with a bi-lobed nucleus, giving the cell a typical “owl’s eyes” appearance. The arrow shows CD15 positive tumor.